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Fructus Viticis methanolic extract attenuates trigeminal hyperalgesia2019-12-02

Fructus Viticis methanolic extract attenuates trigeminal hyperalgesia
in migraine by regulating injury signal transmission


DOI: 10.3892/etm.2019.8201

Abstract.  Migraine, characterized by hyperalgesia of the trigeminovascular system, is
a severe condition that leads to severe reductions in the quality of life. Upon external
stimula?tion, the levels of various neurotransmitters, including aspartic acid (Asp),
glutamic acid (Glu), γ?amino butyric acid (GABA), norepinephrine (NE) and 5?hydrox
ytryptamine (5?HT), are significantly altered; this directly or indirectly promotes
trigeminal hypersensitivity.

 

Acetic acid was purchased from Chengdu Kelong Chemical Reagent Factory.
Chengdu Alfa Biotechnology Co., Ltd. provided casticin, luteolin and 3,6,7?trimethylquercetagetin.

版權所有   成都埃法生物科技有限公司   Copyright ? 2017 All Rights Reserved.   備案號:蜀ICP備17025379號-1

技術支持:庫價化學(KuuJia)

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